Ender's Game by Orson Scott Card - A brilliant young boy is molded into a military leader to save humanity from an alien threat in this classic work of science fiction.
The Girls by Lori Lansens - Can you really know another person, even if you spend every waking moment with her? Ruby and Rose are conjoined twins narrating the story of their remarkable shared lives.
The Wee Free Men by Terry Pratchett - When the Queen of the Fairies steals her whiny little brother, witch-in-training Tiffany Aching joins with a rowdy group of tiny kilted men to rescue him.
Wintersmith by Terry Pratchett - When junior witch Tiffany Aching joins a dance of the seasons, she attracts the attention of the Wintersmith and needs all of her ingenuity to rebalance the world before it plunges into permanent winter.
I Shall Wear Midnight by Terry Pratchett - Tiffany Aching, Chalk witch, must cope not only with everyday human failings of the people she watches over, but also the rise of an old evil that is out to destroy witches everywhere.
Which Witch? by Eva Ibbotson - Kindly white witch Beladonna has never been able to do black magic, but when the handsome wizard Arriman sets a contest to find the wickedest witch to be his bride, she is determined to give it her best shot.
The City and the Stars by Arthur C. Clarke - In the immortal city of Diaspar nothing changes - until Alvin is created, the first new human in eons, and the first to ask what lies beyond the city's gilded walls.
Monstrous Regiment by Terry Pratchett - Polly cuts off her hair, names herself Oliver, and joins the army of Borogravia - only to discover that she may not be the only one in her regiment of fresh-faced recruits hiding a secret.
Cordelia's Honor by Lois McMaster Bujold - When an attack leaves her stranded on an uninhabited planet, Cordelia Naismith is forced to travel with Aral Vorkosigan, a man better known as the Butcher of Komarr.
Gods Like Us by Ty Burr - Charting the highs and lows of stardom from the silent idols to today's over-exposed pantheon of celebrities, film critic Ty Burr examines the cultural history of Hollywood fame.
Beating Back the Devil by Maryn McKenna - The Center for Disease Control has been on the front lines fighting the effects of war, terrorism, and disease since 1946; this book recounts many of their most important cases.
The Mysterious Howling by Maryrose Wood - A young governess enters the mysterious Ashton Place to care for three children raised by wolves - can she tame their howling and squirrel-chasing ways?
A Supposedly Fun Thing I'll Never Do Again by David Foster Wallace - This keenly observed series of essays encompasses tennis in Tornado Alley, television's effect on fiction, the films of David Lynch, the Illinois State Fair, and a superbly snide summary of a supposedly fun Caribbean cruise.