Showing posts with label Science. Show all posts
Showing posts with label Science. Show all posts

Friday, August 30, 2013

Ignorance

Ignorance: How it drives scienceIgnorance: How it drives science by Stuart Firestein
My rating: 3 of 5 stars

This is a short essay with case studies by scientist Stuart Firestein about the power of ignorance in advancing scientific knowledge and inquiry. Firestein suggests that the right kind of ignorance is actually more important to scientists than factual knowledge. The facts may mislead us, or be themselves wrong: therefore being able to ask the right questions is essential.


Firestein discusses what he calls strategies of ignorance, which scientists use to help them decide where to start looking for new knowledge. He ends the book with four brief and fascinating case studies in very different fields that all indicate the new frontiers of ignorance that scientists are broaching. It's all written to illuminate the process of scientific inquiry to laypeople. For a taste of the book, check out his 2013 TED Talk "Celebrating Ignorance".

The first connection I made while reading was to a book I often think of: So Many Books by Gabriel Said. It's another small punch in the gut, giving me a powerful sense of the scale of my own ignorance of an area I know a lot about: literature and book publishing.

Reading Ignorance and So Many Books as a librarian whose job it is to "find the answers", was a helpful reminder about the vagaries of human knowledge. Highly trained scientists spend their entire careers working on problems that may or may not have solutions - but no one will know until someone is curious enough to look. In reference librarianship, the first thing you are taught is how to conduct a reference interview to get at the patron's real question, which is almost never the first thing they ask. (Finding the real question, in fact, often takes longer than finding the answer.)

Firestein points to a microhistory by Mary Poovey called A History of the Modern Fact, which is another good follow-up for those interested in how we came to our modern definition of knowledge.

Quotable:
"Knowledge is a big subject. Ignorance is bigger. And it is more interesting." - 10

"Curiously, as our collective knowledge grows, our ignorance does not seem to shrink. Rather, we know an ever smaller amount of the total, and our individual ignorance, as a ratio of the knowledge base, grows." - 13

"Libraries are both awe inspiring and depressing. The cultural effort they represent, to record over generations what we know and think about the world and ourselves, is unquestionably majestic, but the impossibility of reading even a small fraction of the books inside them can be personally dispiriting." - 14

"The universe is not deterministic; it is probabilistic, and the future can't be predicted with certainty." - 36

"This is an example of why the brain is so poor an instrument for understanding how it works - at least through introspection. You can think about it all you want, and you will never get access to what your brain is doing computationally at any given moment. You only have access to a result, a behavior or perception, that could have been reached in numerous indistinguishable ways." - 147

"We often use the word ignorance to denote a primitive or foolish set of beliefs. In fact, I would say that 'explanation' is often primitive or foolish, and the recognition of ignorance is the beginning of scientific discourse. When we admit that something is unknown and inexplicable, then we admit that it is worthy of investigation." - 167

Friday, June 29, 2012

Giving Me A Heart Attack


While watching this, I was doing what my mom does during horror movies - holding my hand over my mouth. The lava at Nyiragongo moves at 60 miles an hour!

Via TYWIKIWDBI.

Wednesday, May 23, 2012

Phineas Gage

Phineas Gage with the tamping rod that was driven through his head

Phineas Gage was an unfortunate man, but it's an ill wind that blows no good. His brain injury, sustained in 1848 when a tamping iron blew through his skull, left him alive but changed his personality.

Below is a digital reconstruction of his injury, showing what parts of his brain may have been affected by his accident. For more details on Gage and the reconstruction, check out this Guardian article by Mo Costandi. Even if it's not entirely accurate, it's still a beautiful graphic.

Phineas Gage’s Connectome
In 1848, railroad worker Phineas Gage had a 3.5-foot, 13 pound tamping iron blown through the front of his skull in a construction accident. Hell of a way to start your Wednesday (yes, I checked). He survived.
The story of Phineas Gage is now the stuff of legend, taught to first-year neuroscience students around the world. How did this man survive a rod through the frontal lobe? Doctors that wrote of him later spoke of extreme behavioral changes, a man who was “. . . fitful, irreverent, indulging at times in the grossest profanity (which was not previously his custom), manifesting but little deference for his fellows”. 
Unfortunately, the legend of Phineas Gage’s post-injury brain is largely exaggerated, or at least based on rather thin evidence. But still, he was still a changed man, even if not in the extreme ways his legend suggests.
UCLA’s Jack Van Horn has reconstructed a model of Phineas Gage’s connectome. In the image above, the lower left image shows the “connectogram” of 110 healthy right-handed males, the major highways and byways between brain regions (the brain stem is at 6 o’clock, left and right hemispheres at 9 and 3 o’clock). The lower right image shows the connections that were likely disrupted by the iron spike through Gage’s frontal lobe.
Mo Costandi has a great write-up that you should check out. We now have a map of the damage to Gage’s brain. But do we really know any more about his supposed behavioral changes? Thanks to the exaggerations and sideshow mentality of those who studied hm while alive, likely not.
BONUS: Be sure to check out Robert Krulwich and Carl Zimmer moderating this debate on how much stock we should put in the connectome.
(via Neurophilosophy blog)

Thursday, May 17, 2012

A Vision of the Future

We know that not all visions of the future offer comfort.

This one, from game designer Jesse Schell, could be the basis of a credible near-future science fiction universe (dibs on the idea - though I suppose it's partly covered by the YA novel Feed by M.T. Anderson). It could be enabled by the weird tech glory of Google's new virtual reality glasses.



Found via TED Talks.